CBD Bioavailability Chart

CBD Bioavailability Chart

When you consume hemp-based products for health purposes, you should become familiar about bioavailability.

What does bioavailability mean?

Bioavailability refers to the proportion of the substance that becomes available to the target tissue after administration. An intravenous dose is considered 100% bioavailable since it goes into the bloodstream directly. Any substance that is administered through other methods is going to be less bioavailable.

CBD Bioavailability Chart

Why bioavailability matters?

I get asked frequently about how much CBD to take. CBD oil comes in a variety of concentrations- we have six different strengths under our brand alone. How much cannabinoid the body is actually utilizing isn’t strictly determined by how much you are taking. This is when bioavailability comes into play.

Bioavailability of edibles (4-20%)

Any CBD product that is eaten or drank must pass through the digestive system and liver. This process has significant waste, which is why only 4-20% of the cannabinoid is available for use. Even though you’ll need a significant amount of CBD to be effective, it is still a desirable way to take CBD since it’s convenient.

Bioavailability of sublingual tinctures and oils (20-50%)

Holding CBD under your tongue allows it to be absorbed directly into the blood stream through the thin membrane, bypassing the digestive system. Hence boosting the bioavailability significantly.

Bioavailability of CBD Topicals (5-10%)

CBD infused creams and lotions are a rising beauty trend. Of all the ways to consume cannabinoids, topical is perhaps the least bioavailable way. Cannabinoids are highly hydrophobic, meaning it would want to go to areas where there’s more fat, so the skin itself is a barrier. However, there are other ingredients in the topical that may aid in delivery and effectiveness of cannabinoids. Our Releaf Salve has a blend of essential oils and menthol that works synergistically with CBD. Many have found it useful for pain, muscle tension and arthritis.

Love and light,

Mimi May

  1. Pharmacokinetics of cannabinoids https://pubmed.ncbi.nlm.nih.gov/16237477/


This content is for educational purposes only. The information provided is derived from research gathered from external sources.

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